By J. Bart Classen, MD
Classen Immunotherapies, Inc.
3637 Rockdale Road, Manchester, MD 21102
E-mail: classen@vaccines.net

Citation:  Classen JB. COVID-19 RNA Based Vaccines and the Risk of Prion Disease. Microbiol Infect Dis. 2021; 5(1): 1-3.

ABSTRACT

Development of new vaccine technology has been plagued with problems in the past. The current RNA based SARS- CoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing. In this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine recipients. The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations. The results indicate that the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations. In the current analysis a total of sixteen UG tandem repeats (ΨGΨG) were identified and additional UG (ΨG) rich sequences were identified. Two GGΨA sequences were found. Potential G Quadruplex sequences are possibly present but a more sophisticated computer program is needed to verify these. Furthermore, the spike protein, created by the translation of the vaccine RNA, binds angiotensin converting enzyme 2 (ACE2), a zinc containing enzyme. This interaction has the potential to increase intracellular zinc. Zinc ions have been shown to cause the transformation of TDP-43 to its pathologic prion configuration. The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases. The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.

Keywords
COVID-19, Vaccines, Diabetes, Immunity.

Introduction
Vaccines have been found to cause a host of chronic, late developing adverse events. Some adverse events like type 1 diabetes may not occur until 3-4 years after a vaccine is administered [1]. In the example of type 1 diabetes the frequency of cases of adverse events may surpass the frequency of cases of severe infectious disease the vaccine was designed to prevent. Given that type 1 diabetes is only one of many immune mediated diseases potentially caused by vaccines, chronic late occurring adverse events are a serious public health issue.

The advent of new vaccine technology creates new potential mechanisms of vaccine adverse events. For example, the first killed polio vaccine actually caused polio in recipients because the  up  scaled  manufacturing  process  did  not  effectively  kill the polio virus before it was injected into patients. RNA based vaccines offers special risks of inducing specific adverse events. One such potential adverse event is prion based diseases caused by activation of intrinsic proteins to form prions. A wealth of knowledge has been published on a class of RNA binding proteins shown to participating in causing a number of neurological diseases including Alzheimer’s disease and ALS. TDP-43 and FUS are among the best studied of these proteins [2].

The Pfizer RNA based COVID-19 vaccine was approved by the US FDA under an emergency use authorization without long term safety data. Because of concerns about the safety of this vaccine a study was performed to determine if the vaccine could potentially induce prion based disease.

Methods
Pfizer’s RNA based vaccine against COVID-19 was evaluated for the potential to convert TDP-43 and or FUS to their prion based disease causing states. The vaccine RNA was analyzed for the presence of sequences that can activate TDP-43 and FUS. The interaction of the transcribed spike protein with its target was analyzed to determine if this action could also activate TDP-43 and FUS.

By Mordechai Sones
AmericasFrontlineDoctors.org

America's Frontline Doctors (AFLDS) today filed a motion in the U.S. District Court for the Northern District of Alabama requesting a temporary restraining order against the emergency use authorization (EUA) permitting using the COVID-19 vaccines in children under the age of 16, and that no further expansion of the EUAs to children under the age of 16 be granted prior to the resolution of these issues at trial.

The case will challenge the EUAs for the injections on several counts, based on the law and scientific evidence that the EUAs should never have been granted, the EUAs should be revoked immediately, the injections are dangerous biological agents that have the potential to cause substantially greater harm than the COVID-19 disease itself, and that numerous laws have been broken in the process of granting these EUAs and foisting these injections on the American people.

AFLDS Founder Dr. Simone Gold spoke about the reasons for filing the motion: "We doctors are pro-vaccine, but this is not a vaccine," she said. "This is an experimental biological agent whose harms are well-documented (although suppressed and censored) and growing rapidly, and we will not support using America’s children as guinea pigs."

She continued: "We insist that the EUA not be relinquished prematurely; certainly not before trials are complete - October 31, 2022 for Moderna and April 27, 2023 for Pfizer. We are shocked at the mere discussion of this, and will not be silent while Americans are used as guinea pigs for a virus with survivability of 99.8% globally and 99.97% under age 70.

"Under age 20 it is 99.997% - 'statistical zero'.

Children’s Health Defense and Millions Against Medical Mandates invite parents, healthcare practitioners, military members and others to comment on their petition calling on the U.S. Food and Drug Administration to immediately remove COVID vaccines from the market.

ChildrensHealthDefense.org

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Amid growing safety concerns, Robert F. Kennedy, Jr. and Dr. Meryl Nass, on behalf of Children’s Health Defense (CHD), filed a Citizen Petition with the U.S. Food and Drug Administration (FDA) asking the agency to immediately revoke the Emergency Use Authorizations (EUAs) for COVID vaccines and to refrain from licensing them.

Millions Against Medical Mandates (MAMM), a coalition of health freedom organizations and individuals, joins CHD and other vaccine safety and health freedom groups in inviting the public, including healthcare workers, parents and military members, to submit comments on the petition.

CHD compiled and submitted 72 references supporting the request for revocation and restraint. To read the full petition text, download it from the FDA website or read the full petition here — then submit your comments using this form.

According to the most recent Centers for Disease Control and Prevention’s Vaccine Adverse Event Reporting System data, there have been 192,954 reported adverse events following COVID vaccination, including 4,057 deaths between Dec. 14, 2020 and May 7, 2021.

These numbers stand in stark contrast to those reported following the aborted 1976 swine flu vaccine campaign that ended abruptly following approximately 30 reported deaths and 400 cases of Guillain–Barré syndrome.

Citing the extremely low risk to children from COVID, the petition calls on the FDA to immediately refrain from allowing minors to participate in COVID vaccine trials and to immediately revoke all EUAs permitting vaccination of children under 18.

“It’s time for the FDA to make a dramatic course correction before more deaths and injuries occur,” said Maureen McDonnell, MAMM founder.

This video reveals that 100% of the people in this particular hospital for "COVID" illness, are people who got BOTH vaccine shots!  So it seems from this that EITHER: 1) The so-called "vaccine" does NOT protect from COVID, OR; 2) The vaccine is making people sick with COVID-like Symptoms!  Either way, folks who have NOT taken the "jab" should give very serious thought to NOT getting it; it seems from this video, the shots ARE NOT EFFECTIVE AT ALL!  NOT SAFE AND NOT EFFECTIVE!

Editor's Note: The notion that "vaccines are safe and effective" is PURE MYTH generated by Big Pharma with decades of brainwashing propaganda.  Once the vaccine industry finagled total immunity protections under the false claim that the benefits far outweigh the risks, the vaccine industry has ZERO incentive to make products that are safe  AND THEY ARE NOT SAFE OR EFFECTIVE!!

Over 15 million doses of Covid-19 vaccines were halted and trashed after FDA inspectors found ingredients from other vaccines in the Johnson & Johnson jabs, and discovered ‘brown residue’ all over the floors and walls, and open bags of medical waste being dragged around the facility. Talk about dirty vaccines, this is beyond all comprehension. This sounds like some (fast food) chicken processing plant, where the animals wallow in their own feces, infected with pathogens and then end up in everybody’s mouths, except in this case it’s dirty vaccines that end up killing people. No wonder some vaccines list E. coli and urea as “ingredients.”

Article by S.D. Wells from Natural News.

So much for ‘safety and efficacy’ — vaccine ‘science’ is now just dirty and dangerous

This Baltimore factory for J&J Covid-19 vaccine manufacturing was documented by FDA inspectors as being in total disregard for procedures set in place for safety and efficacy. Too bad all these mask-loving Americans can’t watch the video footage of their beloved vaccine scientists and doctors dragging around open bags of medical waste right where they’re concocting the inoculations. Talk about germ paranoia.

FDA inspectors also noted peeling paint, inadequate cleaning, and employees contaminating areas by not following procedures. So far, nothing created at this septic plant has been injected into sheeple arms, yet (doesn’t mean they won’t sell those dirty vaccines to another country). No worries here though, because the eight million doses of the J&J vaccine given to Americans came from Europe, though there’s no telling how many open bags of biomedical waste they’re dragging around in their vaccine dungeons, with feces spread all over the floors and walls.

Editor's Note:  This article was originally published back in 2017 and NOTHING has changed with regards to this dangerous technology except corrupt government green-lighting it all despite the unresolved dangers.

By Damian Garde
StatNews.com
 

SAN FRANCISCO — Moderna Therapeutics, the most highly valued private company in biotech, has run into troubling safety problems with its most ambitious therapy, STAT has learned — and is now banking on a mysterious new technology to keep afloat its brash promise of reinventing modern medicine.

Exactly one year ago, Moderna CEO Stéphane Bancel talked up his company’s “unbelievable” future before a standing-room-only crowd at the annual J.P. Morgan Healthcare Conference here. He promised that Moderna’s treatment for a rare and debilitating disease known as Crigler-Najjar syndrome, developed alongside biotech giant Alexion Pharmaceuticals, would enter human trials in 2016.

It was to be the first therapy using audacious new technology that Bancel promised would yield dozens of drugs in the coming decade.

But the Crigler-Najjar treatment has been indefinitely delayed, an Alexion spokeswoman told STAT. It never proved safe enough to test in humans, according to several former Moderna employees and collaborators who worked closely on the project. Unable to press forward with that technology, Moderna has had to focus instead on developing a handful of vaccines, turning to a less lucrative field that might not justify the company’s nearly $5 billion valuation.

“It’s all vaccines right now, and vaccines are a loss-leader,” said one former Moderna manager. “Moderna right now is a multibillion-dollar vaccines company, and I don’t see how that holds up.”

By Mike Whitney
UNZReview.com

The risk-benefit calculus is therefore clear: the experimental vaccines are needless, ineffective and dangerous. Actors authorizing, coercing or administering experimental COVID-19 vaccination are exposing populations and patients to serious, unnecessary, and unjustified medical risks.” Doctors for Covid Ethics, April 29, 2021

An explosive new study by researchers at the prestigious Salk Institute casts doubt on the current crop of gene-based vaccines that may pose a grave risk to public health. The article, which is titled “The novel coronavirus’ spike protein plays additional key role in illness”, shows that SARS-CoV-2’s “distinctive ‘spike’ protein”..”damages cells, confirming COVID-19 as a primarily vascular disease.” While the paper focuses strictly on Covid-related issues, it unavoidably raises questions about the new vaccines that contain billions of spike proteins that could greatly increase the chances of severe illness or death. Here’s an excerpt from the article dated April 30, 2021:

“In the new study, the researchers created a “pseudovirus” that was surrounded by SARS-CoV-2 classic crown of spike proteins, but did not contain any actual virus. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal model—proving that the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls. (Note– “Vascular endothelial cells line the entire circulatory system, from the heart to the smallest capillaries.”)

The team then replicated this process in the lab, exposing healthy endothelial cells (which line arteries) to the spike protein. They showed that the spike protein damaged the cells by binding ACE2. This binding disrupted ACE2’s molecular signaling to mitochondria (organelles that generate energy for cells), causing the mitochondria to become damaged and fragmented.

Previous studies have shown a similar effect when cells were exposed to the SARS-CoV-2 virus, but this is the first study to show that the damage occurs when cells are exposed to the spike protein on its own.” (“The novel coronavirus’ spike protein plays additional key role in illness”, Salk.edu)

The new research paper is the equivalent of a hydrogen bomb. It changes everything by confirming what vaccine critics have been theorizing for months but were unable to prove.

Now there is solid evidence that:

1. Covid-19 is primarily a disease of the vascular system (The vascular system, also called the circulatory system, is made up of the vessels that carry blood and lymph through the body.) and not the respiratory system.
2. The main culprit is the spike protein. (Spike protein–“a glycoprotein that protrudes from the envelope of some viruses” Merriam-Webster “Like a key in a lock, these spike proteins fuse to receptors on the surface of cells, allowing the virus’s genetic code to invade the host cell, take over its machinery and replicate.” Bruce Lieberman)

Simply put, if Covid-19 is primarily a vascular disease and if the main instrument of physical damage is the spike protein, then why are we injecting people with billions of spike proteins?

Here’s how architect and author, Robin Monotti Graziadei, summed up these developments:

Partial Transcript

“So, we have been told for the last year, that the only role the spike protein was supposed to play was to enter the human cells. (But) It’s clear, that that is not what they do, (since) they give you illness, vascular illness. Vascular illness can have many manifestations. They can include sinus vein thrombosis, blood clots, bruising, and longer-term conditions. Do you think it’s a good idea to bypass the first (defenses) of your immune system, …and inject… trillions of spike proteins in your cells given the information that has just been released by the Salk Institute? Think about it….

Salk Institute researchers have told us –without any ambiguity– that the spike protein is a fundamental part of the Covid-19 disease. Yes, it’s true that the spike protein with the N-protein, will not replicate. However, trillions (of these proteins) induced by the vaccine injection have the capacity to create damage in your vascular system. This is what the study says and what has been published by an extremely important center for biological studies. This is not a conspiracy theory. I think, at this stage, there is enough information to consider whether we will be told the truth in the coming days, because such information should be on the cover of every newspaper and the top story on every news channel. And what they should say is this: “The fundamental and technological basis –on which all of the vaccines that were distributed in the West– is flawed. We thought that the spike protein would only enter the cells to create antibodies so if you faced the wild virus, it would not latch onto your cells, however, we were wrong. We were wrong because the spike protein in itself, creates disease, and if you inject trillions of them into a human body, there will be manifestations of disease in many cases.” It is not safe to inject trillions of spike proteins into a muscle, because it bypasses layers of your immune system which could have potentially neutralized the virus… By crossing the threshold of the human body through the injection of these compounds, you are not giving your immune system the chance to mount a strong enough response to the spike protein in order to neutralize it. (The vaccine) will have this disease-creating spike protein in it if you agree (to take) any of these vaccines. ….It is now up to us to try to fix the mistake they have made.”

By Corye Lynn
Solari.com

Introduction

All over America, employees are facing a very tough decision right now. Although some wish to accept a Covid-19 injection, many do not. The problem is that a growing number of employers are trying to deny employees’ right to choose and their right to bodily integrity by requiring the vaccines as a condition of employment. In the United States and other jurisdictions, that is a violation of the law. It is also a violation of fundamental human and religious rights.

In the U.S., the provisions of the 2005 Public Readiness and Emergency Preparedness (PREP) Act and a February 2020 declaration by the Secretary of the Department of Health and Human Services (HHS) mean that pharmaceutical companies cannot be held liable for injuries or deaths caused by the Covid-19 injections.¹ However, other companies, institutions, and individuals can be held liable. This form is designed as a tool that employees can use to provide this critical information to employers, and to insist on a signature from the employer’s representative that holds the company liable if the employee should decide to accept the required experimental Covid-19 injection.

We are already seeing that health care providers are refusing service to individuals injured by the Covid-19 injections, and health and life insurance companies are declining coverage for vaccine-related injuries and deaths on the grounds that the injections are investigational vaccines allowed under Food and Drug Administration (FDA) emergency use authorization (EUA) but not otherwise approved or licensed.² This denial of care and coverage poses a serious threat to the physical and financial well-being of employees presented with a requirement to get a Covid injection—perhaps even more so than the possibility of losing their job for not being vaccinated.

Reviewing this form with employers may open their eyes to the regulations in place and the liability they may face (that they may otherwise not be aware of). Everyone should consider reviewing the form with their employer as well as sharing it with co-workers. This could result in a positive impact for employees and could be a game-changer. Alternatively, if the employer representative refuses to sign the form, that may be an indicator of their concern about potential liability and should prompt an immediate discussion about how the employee can continue working for the company without being injected.

If you find yourself in a predicament with a company that refuses to hear you out, does not provide you with required information, or threatens termination of your employment, here are a few potential resources for contacting attorneys. America’s Frontline Doctors provides an intake form on their site that you can fill out and submit, and they will search for an attorney in your area who is taking on this type of case.³ There is a small fee for the search, and of course, attorneys have their own fees. The legal team of the Informed Consent Action Network (ICAN) is offering to assist employees/students who are being required by an employer/school to receive the Covid-19 injection.⁴ If you find yourself needing a vaccine injury case attorney, you might also try looking through this state list.⁵

By Ethan Huff
NewsTarget.com

The latest “conspiracy theorist” to come forward and warn about particulate shedding from those who were recently “vaccinated” for the Wuhan coronavirus (Covid-19) is none other than Pfizer itself.

The pharma giant’s own documents openly admit that people who were recently jabbed for the Chinese virus can transmit whatever is contained in the syringe to others, including through skin contact.

“An occupational exposure occurs when a person receives unplanned direct contact with a vaccine test subject, which may or may not lead to the occurrence of an adverse event,” the Pfizer document warns.

“These people may include health care providers, family members, and other people who are around the trial participant.”

In other words, there is something contained in the injections that cause the injected to become “superspreaders.” Pfizer does not indicate what this is, however it does warn that the culprits are people who were recently injected.

Such transmission might occur from a simple handshake or a hug. It will almost certainly happen during sexual activity, which means those who are wanting to avoid contracting whatever poison is inside these things should be sure that their partner did not receive an injection.

The document goes on to reveal that vaccinated women who are pregnant could suffer spontaneous abortions and other reproductive problems – and unvaccinated people who come into contact with them could as well.

Vaccinated mothers can also pass whatever is contained in the Pfizer injection to their babies through tainted breast milk as well.

In this presentation with The New American magazine's Alex Newman, Dr. Carrie Madej explains that the elites peddling the COVID shots are also pushing transhumanism--and the two are closely related. Genetic modifications and new technologies are on the verge of changing what it means to be human, and the elites are really pushing the boundaries. Don't miss this critically important presentation by one of the most important doctors speaking out on these issues publicly.